This chapter provides an essential overview of facial aesthetics and cosmetic injection procedures, with emphasis on the anatomical knowledge and technical precision required for safe, effective outcomes. It begins by outlining the clinical uses of neurotoxin injections and the importance of understanding facial muscle structure, function, and movement patterns to achieve accurate placement and natural-appearing results. Key technical tips are presented to guide dosing, injection angles, and treatment planning, followed by evidence-based neurotoxin aftercare recommendations. This chapter then reviews the role of dermal fillers in restoring facial volume, enhancing definition, and correcting age-related contour changes across commonly treated regions. Practical guidance is provided on product selection, depth of placement, and anatomical considerations for each area. Technical pearls for optimizing filler procedures are included, along with detailed aftercare instructions to support treatment longevity and minimize complications. Together, these sections offer a concise yet comprehensive foundation for practitioners seeking to refine their approach to modern facial injectable treatments.