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Functional pancreatic endocrine neoplasms are a diverse group of malignant and non-malignant neoplasms (insulinoma, gastrinoma, VIPoma, glucagonoma, and somatostatinoma) all with varying clinical manifestations. This chapter provides an understanding of genetic predispositions (i.e., MEN1) and clinical manifestations of functional pancreatic endocrine neoplasms that will help guide practitioners in their workup and management.

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Functional Pancreatic Endocrine Neoplasia Syndromes

  • 章节

  • 发表日期：

    2026年

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  • Colette Brottman,
  • Jeffrey Matthews

摘要

Functional pancreatic endocrine neoplasms are a diverse group of malignant and non-malignant neoplasms (insulinoma, gastrinoma, VIPoma, glucagonoma, and somatostatinoma) all with varying clinical manifestations. This chapter provides an understanding of genetic predispositions (i.e., MEN1) and clinical manifestations of functional pancreatic endocrine neoplasms that will help guide practitioners in their workup and management.