Digital technologies with cutting-edge disruptive innovation have developed an ecosystem of dependence on technologies for today’s contemporary business, particularly in the unpredictable nature of business. AI is considered a boon by most industry leaders (McKinsey & Company, 2023). On the contrary, the trustworthiness of AI is at the centre of research across the business domain. Notwithstanding, the indispensable role of AI in business further enhances the scope of research for AI’s predictive role in business sustainability. Sustainability has been a buzzword ever since environmental hazards overshadowed and outweighed the economic value of businesses (World Economic Forum Global Risk Report, 2020). Under these prevailing circumstances, it has become imperative to find the benefits of applying AI in business to mitigate the negative impact of business on environmental disasters. Therefore, this qualitative research further explores the scope of future research on AI applications, focusing on their trustworthiness and effectiveness in business operations, to mitigate the risk of ecological and environmental damage. Moreover, this theme-based qualitative study has opened up multiple dimensions of research on sustainable business practices, utilizing AI prediction to inform decisions based on an extensive literature review. This qualitative research proposes numerous directions for further exploration of the various paths (themes) of AI application in business, aiming to introduce sustainable practices across diverse business sectors.