Non-antimicrobial Management of Recurrent Urinary Tract Infection
摘要
Recurrent Urinary Tract Infections (UTIs) are defined as two episodes in six months or three episodes in a year. Women are sixfold more likely to suffer UTIs compared to men and half of all women have been estimated to experience a UTI in their lifetime, with up to 50% of these having recurrence within 6 months. The availability of effective antibiotics is diminishing due to the rising rates of antimicrobial resistance. Non-antibiotic treatments for prevention of recurrent UTI can potentially minimise development of antimicrobial resistance in bowel reservoirs and are an attractive option for prevention of recurrent UTIs. Non-antibiotic preventative treatments include promoting fluid intake, oestrogens, immune-active prophylaxis, probiotics, D-mannose, methenamine hippurate, and intravesical therapies.