The healthcare system is evolving from centralised infrastructures to self-organising healthcare ecosystems that utilise the Internet of Medical Things (IoMT), Artificial Intelligence (AI), and distributed data analytics. These latest technologies enable the real-time monitoring of patients, allowing for diagnosis from a distance or virtually, as well as informed medical decisions based on patient requirements. However, by created new cybersecurity problems that did not exist earlier. Ransomware, data breach threats, and insider threats have become the most common attacks on sensitive records of patients. This becomes a threat to people’s privacy, integrity and affects trust in the digital healthcare systems. Blockchain technology provides a strong base to protect medical data, to ensure the immutability of data, and also provides permission to the people who have their data. This chapter highlights the blockchain technology that helps to protect the self-organising healthcare networks that focus on protecting the data of patients, to manage identities safely, also to allow the different systems to operate together. This chapter defines the blockchain-enabled architecture for hospital cybersecurity, to analyse real-world deployments, also assess difficulties such as regulatory compliance, scalability, assessing difficulties such as scalability, regulatory compliance, and energy efficiency. This chapter explains the ways to improve trust, resilience, and security in the next generation medical systems that combine blockchain with self-organising healthcare.