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Physical activity is well known to play important roles in controlling lipid metabolism and decreasing cardiovascular disease (CVD) risk. The present study is designed to explore the effect of regular exercise on cholesterol profiles by comparing trained and untrained women between the ages of 35–45 years. This descriptive comparative study collected information from 100 females, randomly sampled and divided into two distinct groups according to their self-declared level of physical activity. Blood samples for Total Cholesterol (TC), Low-Density Lipoprotein (LDL), and High-Density Lipoprotein (HDL) were measured meticulously with High-Performance Liquid Chromatography (HPLC). Results showed (p < 0.001) that trained women had significantly better cholesterol profiles with lower values of LDL and TC levels and significantly higher values in HDL compared to untrained women. These results were also supported by correlation analysis, illustrating a strong inverse relationship between exercise frequency and LDL levels (r = −0.72, p < 0.01), and a significant positive correlation with HDL (r = 0.68, p < 0.01).Correlation analysis also supported these results, showing a strong negative relationship between exercise frequency and LDL levels (r − 0.72, p −0.01) and a strong positive relationship with the HDL levels (r − 0.68, p − 0.01). These results highlight the very strong impact of regular exercise on the process of lipid metabolism, which makes it one of the promising approaches to cardiovascular disease prevention. The stable cohort of the study and the high performance indicators also give strong empirical evidence that exercise is an ideal first line behavioral intervention in the control of cholesterol, especially among the middle aged women that are in their menopause and have undergone hormonal and metabolic changes. Moreover, the data can be of great help to clinicians, exercise experts as well as the policymakers in the health sector and it should be highlighted the need to increase educational efforts and organized exercise programs among this group.

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Comparison of Blood Cholesterol Levels Between Trained and Untrained Women Aged 35–45 Years

  • 会议论文

  • 发表日期：

    2026年

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  • Omar Khalid Yasir,
  • Zuhad Fawzi Naji,
  • Saleh Mahdi Mukheef,
  • Mustafa Ahmed Obaid,
  • Abbas Hussein Khalifa

摘要

Physical activity is well known to play important roles in controlling lipid metabolism and decreasing cardiovascular disease (CVD) risk. The present study is designed to explore the effect of regular exercise on cholesterol profiles by comparing trained and untrained women between the ages of 35–45 years. This descriptive comparative study collected information from 100 females, randomly sampled and divided into two distinct groups according to their self-declared level of physical activity. Blood samples for Total Cholesterol (TC), Low-Density Lipoprotein (LDL), and High-Density Lipoprotein (HDL) were measured meticulously with High-Performance Liquid Chromatography (HPLC). Results showed (p < 0.001) that trained women had significantly better cholesterol profiles with lower values of LDL and TC levels and significantly higher values in HDL compared to untrained women. These results were also supported by correlation analysis, illustrating a strong inverse relationship between exercise frequency and LDL levels (r = −0.72, p < 0.01), and a significant positive correlation with HDL (r = 0.68, p < 0.01).Correlation analysis also supported these results, showing a strong negative relationship between exercise frequency and LDL levels (r − 0.72, p −0.01) and a strong positive relationship with the HDL levels (r − 0.68, p − 0.01). These results highlight the very strong impact of regular exercise on the process of lipid metabolism, which makes it one of the promising approaches to cardiovascular disease prevention. The stable cohort of the study and the high performance indicators also give strong empirical evidence that exercise is an ideal first line behavioral intervention in the control of cholesterol, especially among the middle aged women that are in their menopause and have undergone hormonal and metabolic changes. Moreover, the data can be of great help to clinicians, exercise experts as well as the policymakers in the health sector and it should be highlighted the need to increase educational efforts and organized exercise programs among this group.