Psychosocial adjustment refers to the influence of psychosocial factors on the quality of life (QoL), which is adversely affected in individuals with visual impairment (VI) due to emotional distress, social isolation, and low self-efficacy. The objective of this study is to assess the influence of a systematic psychological accompaniment agenda in improving the QoL of visually impaired patients. The study employed a pre-test and post-test experimental design over a 3-month intervention period during which participants underwent psychological supports on emotional resilience, social integration, and cognitive restructuring. QoL was measured by the World Health Organization QoL scale (whoqol-bref) pre- and post-intervention. Statistically significant improvements were found, with mean QoL scores rising from 161.3 to 193.8, paired T-test P-value 0.000; thus, the program is effective. These results emphasize the need for psychological interventions to be provided for visually impaired individuals and suggest that their long-term enactment and integration of new technological tools could be more valuable for their welfare. This study contributes empirical evidence for policymakers and rehabilitative specialists and mental health professionals for designing inclusion-support programs for the disabled people.