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The human microbiome consists of a diverse array of bacteria, viruses, fungi, protozoa, and archaea found throughout the body. Most of these microbes are harmless and contribute to essential bodily processes, helping to maintain homeostasis by supporting biological functions and preventing the overgrowth of harmful microbes (Lloyd-Price et al., 2016). The composition of the microbiome can be influenced by factors such as lifestyle, diet, environment, and overall health (Fig. 1). Many tribes such as the Navajo (Diné) embrace a similar core cultural concept known as “Walk in beauty” and living “Hozho,” which emphasizes the importance of balance and harmony within oneself, with others and the surroundings (Kahn-John Diné & Koithan, 2015). Another example of this concept is also reflected in the Hopi beliefs where the way of life revolves around harmony with Nature and all in the universe is sacred and interconnected. Within each person, this balance includes both good and bad cells, as well as beneficial and harmful microbes that coexist in the body.

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The Microbiome, Cancer, and Health Disparities: Implications for Native American Communities in the Southwest

  • 章节

  • 出版模式：

    开放获取

  • 发表日期：

    2026年

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  • Krystal Charley,
  • Nicole Jimenez,
  • Paweł Łaniewski,
  • Melissa Herbst-Kralovetz,
  • Emily Cope,
  • Fernando Monroy,
  • Jani Ingram,
  • Naomi Lee

摘要

The human microbiome consists of a diverse array of bacteria, viruses, fungi, protozoa, and archaea found throughout the body. Most of these microbes are harmless and contribute to essential bodily processes, helping to maintain homeostasis by supporting biological functions and preventing the overgrowth of harmful microbes (Lloyd-Price et al., 2016). The composition of the microbiome can be influenced by factors such as lifestyle, diet, environment, and overall health (Fig. 1). Many tribes such as the Navajo (Diné) embrace a similar core cultural concept known as “Walk in beauty” and living “Hozho,” which emphasizes the importance of balance and harmony within oneself, with others and the surroundings (Kahn-John Diné & Koithan, 2015). Another example of this concept is also reflected in the Hopi beliefs where the way of life revolves around harmony with Nature and all in the universe is sacred and interconnected. Within each person, this balance includes both good and bad cells, as well as beneficial and harmful microbes that coexist in the body.