Headache is an essential field within neurology and general medicine, as it is one of the most common neurological complaints and a leading cause of disability worldwide. This chapter provides a comprehensive, question-based overview of the classification, diagnosis, and updated management of headache disorders, as of the year 2025. Thanks to recent research advances in this field, new insights into the pathophysiology of headache disorders have led to a deeper understanding of these disease states, with more targeted pharmaceutical treatments having come to market, in particular for migraine and cluster headache.