This chapter introduces readers to setting up R for statistical analysis, beginning with downloading and installing R base, the core engine for R, and RStudio, a versatile user interface that simplifies statistical analyses and programming tasks. The chapter then guides readers in creating an RMarkdown file to organize and save code for practice exercises throughout the book. Additionally, it provides an overview of R’s Packages and Libraries, essential tools for extending R’s functionality, and concludes by highlighting one of R’s most valuable resources: the supportive community of users who share knowledge and assist with troubleshooting. This chapter equips readers with the foundational tools and understanding needed to begin applying R for statistical tasks efficiently.