The integration of artificial intelligence (AI) into outpatient medical practice opens up new opportunities for improving diagnosis, patient management, and clinical decision-making processes. This chapter examines key applications of AI in outpatient care and draws lessons from previous digital transformation processes in healthcare. AI technologies such as machine learning, natural language processing, and predictive analytics enable more efficient patient data analysis, early detection of disease patterns, and personalized therapy recommendations. However, experience from digital transformation shows that technological innovation alone is not enough: successful implementation requires the adaptation of workflows, the training of medical staff, and the consideration of ethical, legal, and data protection aspects. Interoperability and user-friendly interfaces are crucial to ensuring acceptance and sustainability. In addition, case studies emphasize the importance of a step-by-step, evaluative approach that measures both clinical and organizational effects. Overall, the analysis makes it clear that AI must be viewed not only as a technical tool but also as an integral part of a comprehensive digital strategy. The findings provide practical recommendations for doctors, practice managers, and healthcare systems on how to use the potential of AI in outpatient care effectively and responsibly.