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The RAB family in humans comprises approximately 70 members with about one third localizing to the Golgi apparatus and associated compartments. This significant localization reflects the number and diversity of transport pathways operating within this central cellular hub. We focus in this review on the molecular mechanisms by which RAB GTPases regulate membrane trafficking at the Golgi level.

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The Functions of RAB GTPases at the Golgi Complex

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  • 发表日期：

    2026年

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  • Bruno Goud

摘要

The RAB family in humans comprises approximately 70 members with about one third localizing to the Golgi apparatus and associated compartments. This significant localization reflects the number and diversity of transport pathways operating within this central cellular hub. We focus in this review on the molecular mechanisms by which RAB GTPases regulate membrane trafficking at the Golgi level.