Since buildings contribute to a significant portion of the world’s energy use and greenhouse gas emission, rapid actions for increasing sustainability and energy efficiency is required. Therefore, there is a significant demand for innovative and more energy efficient materials, technologies, and methods that maintain occupants’ comfort. The main goal is to offer a comprehensive guideline for implementing energy-efficiency options that can be used in new and pre-existing buildings. The chapter uses a combined literature analysis so it can investigate new developments in advanced technology like Building Energy Management Systems and sophisticated HVAC controls, also energy-efficient building materials like phase-change energy storage systems and bio-based isolation. Important methodology like case studies and modeling techniques evaluate the impact of these solutions in many functional and climatic situations. According to research it is revealed that using adaptive shading systems, AI-driven energy management, and sustainable materials, can significantly reduce carbon emissions and energy use, and still improve thermal and visual comfort. These observations show us the possibility of specific solutions that can help to meet net-zero energy requirements and promote sustainable urban growth. Also, some recommendations for implementing region-specific energy efficiency strategies to solve the specific challenges are included in the research.