This chapter unifies N-Frame, QBism, and functional contextualism to present a fully observer-centric formulation of quantum mechanics. It demonstrates that quantum probabilities are not intrinsic properties of systems but context-dependent functions shaped by an observer’s internal cognitive state, external measurement setting, and thermodynamic boundary conditions. Building on the Functional Contextualism–QBism Connection Theorem, it reformulates the Born rule as a contextual probability relation and embeds it within an AdS/CFT-like holographic mapping, where the observer’s consciousness defines boundary data for physical reality. The chapter develops a perturbative and non-Hermitian Hamiltonian model linking conscious focus, quantum measurement, and wavefunction actualization, offering testable predictions for Radin-type experiments. Finally, it formalizes the Tri-Aspect Monism equivalence principle through Euler’s identity, showing that mathematics, physics, and phenomenology are unified projections of a single N-Frame manifold that resolves the measurement problem and reframes consciousness as an active participant in quantum evolution.