This research aims to determine the impact of digital transformation on information management in the healthcare sector in Jordan. The sample size was 380 individuals selected through a proportional stratified method. A questionnaire was designed targeting the research sample items, and the response rate was 80.26%. The results showed a positive impact of digital transformation on information management in the healthcare sector in Jordan. This may be due to the enhancement of efficiency and effectiveness in information management by providing modern tools and techniques for analyzing and storing data. The study found that digital transformation had a relative impact weight of 68.8%, indicating a moderate degree of digital transformation, while information management had a relative weight of 75.5%, indicating a significant degree of information management. The researchers recommended the development and improvement of technological infrastructure in hospitals, as well as the enhancement of digital skills and the provision of training programs, which contribute to improving employee performance and enhancing information management, ultimately improving the quality of healthcare services.