The studies of tolerance constantly face specific new issues and challenges. There are many debates about the relationships among pluralism, multiculturalism, and tolerance. One critical study proposes an equal relationship between the tolerator and the tolerated. The legitimacy and necessity of “tolerance” in modern society have been formally confirmed to a certain extent, constituting an essential element of a harmonious society. Through rational, objective, interdisciplinary, and multidimensional comparison and dialogue on tolerance views between the East and the West, we aim to identify and analyze similarities and differences, thereby facilitating a deeper, more specific, and more comprehensive understanding of tolerance. The commonalities between the East and the West in tolerance views primarily manifest in the recognition of the world’s diversity, which constitutes the ontological basis for tolerance. Recognizing the limited facts of cognition constitutes the epistemological basis for the existence of tolerance. The differences in tolerance views between the East and the West are mainly reflected in historical origins, cultural backgrounds, social structures, political systems, ways of thinking and behavior, and other aspects.