Concrete structures are designed to have a service life of many decades but in many cases their durability is affected by external factors, undermining their safety. A lot of studies have focused on the carbonation of concrete and chlorides penetration on the structures. However only a few have combined both. This study aims to investigate the impact of continuous cycle exposure to air-water conditions on concrete specimens, helping us understand the problems that occur in constructions with alternating exposure, such as the splash zone of marine structures. The experimental program involves two mixtures with a combination of CEM II/A-M 42.5N and CEM II/B-M 32.5N and other two with CEM I 42.5R cement. All formulations were subjected to a series of tests to further investigate the effect of concrete synthesis on the durability factors. After exposure to accelerated carbon dioxide and/or chloride environment, the carbonation depth and chloride penetration were experimentally measured on the specimens. The results indicate that the mixtures with CEM I present lower carbonation and chloride penetration depths. Chlorides presence and cement type strongly influence carbonation, and results differ depending on whether the concrete is in dry-wet cycles or solely submerged in water.