The movable weir under study regulates the water level in the river Meuse creating sufficient water depth for inland navigation with larger ship classes. Over 100 years in service, concrete and steel reinforcement quality needs to be assessed for the purpose of remaining service life predictions of the weir in relation to the future expectations for load and climate changes. Consequently, a framework has been developed for condition assessment of the concrete structures by systematic non-destructive concrete quality assessment followed by destructive testing. This paper presents the outcomes obtained from the overall evaluation of weir Sambeek. Results show that the damage degree of the distinct members varies according to the member’s type, presence of reinforcement, water exposure and coating presence. The weir sill and stilling basin are reinforced. The reinforcement is not present in the piers as demonstrated by the ground penetrating radar measurements. Although not allowed according to nowadays design rules, 100 years ago the absence of reinforcement in large hydraulic structures was not uncommon. Major signs of concrete damage were cracks. The major cracks developed at the cold pouring joints. Crack depth measurements noted some cracks deeper than 100 mm. This raises concerns regarding the structural safety of the weir structure. For members where the structural reliability is a concern, first an in-depth numerical study will be made whether complete replacement is necessary, or partial renovation. A detailed material characterization and understanding is needed to be able to draw up a load-resistance model with increased accuracy.