ZincZinc-based alloys are promising biodegradable materials for biomedical applications due to their biocompatibilityBiocompatibility and lower corrosionCorrosion rates compared to magnesiumMagnesium alloys. This study explores a novel approach to developing these biodegradable zincZinc-based alloys through a unique combination of alloy designAlloy design and advanced processing techniques. The goal is to address the key limitations of conventional zincZinc-based biomaterialsBiomaterials. The research focuses on the application of melt spinningMelt spinning followed by hot extrusion to produce Zn–4.1Ag–0.7Cu–0.4Mn–0.03 Mg alloys. These alloys feature fine-grained, homogeneous microstructuresMicrostructure that exhibit superior mechanical propertiesMechanical properties and enhanced corrosionCorrosion uniformity. Specifically, the melt-spun alloy demonstrates an increase in ductility (approximately 16%) while maintaining a high tensile strengthStrength of around 416 MPa. It also shows reduced corrosionCorrosion rates and more uniform degradation compared to its cast counterpart. Achieving this combination of propertiesProperties in zincZinc-based alloys marks a significant advancement for biodegradable cardiovascular stent applicationsStent application.