This study evaluates the potential of fractal analysis to characterize morphological variations in dried blood droplet deposits under different dilution conditions. Samples from a healthy donor and a donor with diabetes and hyperlipidemia were analyzed to examine how dilution influences solute transport and deposit morphology. Fractal dimension-based metrics effectively distinguished morphological patterns shaped by both dilution level and biochemical composition, with high reproducibility under controlled conditions. The analysis also revealed distinct stages of droplet evaporation, including coffee-ring formation, rapid diameter reduction, aggregate development, mobile central structures, and crack propagation. Results support the use of fractal analysis as a robust tool to enhance diagnostic precision in biofluid-based assays, with promising applications in clinical screening.