Estimating earthquake losses in high-risk areas requires assessing both local seismic hazards and building vulnerability. Since evaluating every structure individually is impractical, large-scale studies often rely on macroseismic methods to characterise the vulnerability of entire neighbourhoods. At the same time, numerical modelling of representative buildings provides more detailed insight into structural weaknesses. Combining both approaches enhances the reliability of seismic risk assessments. This methodology is particularly relevant for mid-20th-century social housing in southern Spain, where buildings were constructed with repetitive designs and no seismic provisions. The limited variation between typologies allows macroseismic findings to be extrapolated across entire districts, while detailed numerical analysis of a single representative structure helps refine vulnerability assessments. This study applies both approaches to evaluate the seismic vulnerability of a neighbourhood composed of high-rise reinforced concrete apartment buildings, a common social housing type in the region. First, a macroseismic analysis is conducted using a vulnerability index method adapted by the authors to assess the entire neighbourhood. Then, a detailed numerical assessment is performed on a representative building, using original design drawings from the Municipal Archive to develop a structural model incorporating accurate geometry, materials, and loads. A preliminary analysis using FEA software RFEM 6 is then carried out. Both methods are in good agreement, and confirm the buildings’ high susceptibility to seismic hazards, underscoring the need for further in-depth investigations.