Humans have always relied on nature. However, recent technological advancements and urban expansion have increasingly harmed the environment, disrupted natural cycles, and created ecological challenges in cities. The inevitability of urban development and the utilization of new technologies, alongside the imperative of preserving nature and ensuring environmental sustainability, highlight the necessity of adopting a responsible approach to human-nature relationship and the manner of interventions within it. The human-nature relationship varies based on the worldview and theology adopted by humans. This research aims to address key questions: What are the main approaches to human-nature relationship and how do they affect interventions in nature? Which approach can ensure proper exploitation of nature and the proper use of new technologies, while also ensuring sustainability and maintaining authentic connections with it? Can Islamic theology as a worldview provide a suitable approach to human-nature relationship? and What is its role in creating a sustainable and spiritual urban future in the age of technology? Through content analysis and comparative studies, this study compares different human-nature approaches and evaluates their influence on environmental interventions. Findings reveal the Islamic perspective, termed “Nature-maker” significantly contributes to preserving nature while encouraging communities to embrace beneficial technologies without compromising authentic connections to nature. Islam views the human-environment relationship as a spiritual bond, equating harm to nature with harm to human existence through ontological hierarchies. By adopting this spiritual approach globally, there is potential to resolve or mitigate current ecological crises.