The introduction of autonomous vehicles (AVs) presents significant challenges in achieving optimal thermal comfort for passengers. Conventional air conditioning (AC) systems, which are designed around a fixed, driver-centric layout, are not equipped to handle the diverse in-cabin activities that are characteristic of AVs. This paper presents a comprehensive, survey-based analysis of thermal comfort preferences across three primary activity modes: productivity, entertainment, and relaxation. A review of the fundamental principles of thermal comfort is conducted, and current ventilation strategies are examined with an emphasis on adaptive, personalized climate control and the concept of Non-Driving Related Activities (NDRAs). An extensive online survey is described, and the resulting data indicate a gender difference in thermal sensitivity and local ventilation preferences for NDRAs. The findings underscore the significance of adaptive climate control for future AVs, emphasizing the need for user-centered, energy-efficient solutions.