The chapter explores the integration of fungal and algal treatment systems for wastewater management, addressing the challenges associated with fungal contaminants. Conventional wastewater treatments often struggle with fungal contaminants due to their resilience and ability to form biofilms. Fungal contaminants pose health risks and hinder effective treatment, making their removal a critical concern. The chapter proposes combining fungal and algal systems as a solution, leveraging the strengths of both. Fungi, known for breaking down complex organic pollutants, can degrade materials that traditional methods cannot handle, while algae excel in nutrient removal and oxygen production. This integration allows for enhanced pollutant degradation and nutrient management, offering a dual approach to improving wastewater treatment. The chapter also discusses various integration strategies, such as co-cultivation and sequential processes, emphasizing the importance of optimizing conditions like pH, temperature, and nutrient availability to enhance the system’s performance. Case studies illustrate successful applications of integrated systems in diverse wastewater contexts, demonstrating improvements in treatment efficiency, reduced sludge production, and economic benefits through resource recovery. The chapter concludes that integrated fungal and algal treatment systems represent a promising approach to wastewater management, offering improved efficiency and sustainability. It highlights the need for continued research and innovation to address challenges related to scaling and system optimization, aiming to advance the adoption of these technologies for better environmental outcomes.