Advances in the treatment of HF and early interventions to prevent clinical decompensation delay disease progression and improve survival. After initial evaluation and the implementation of guideline-directed medical therapy, outpatient HF management strategies focus on the maintenance of patient stability. Multidisciplinary disease-management HF programs may help improve HF patient outcomes, including decreased symptoms, improved quality of life, reduced rates of hospital admission, and decreased healthcare costs. The principals of effective HF care include: a patient-centered multidisciplinary approach, rigorous adherence to evidence-based treatment through written protocols, early detection of exacerbations, development of individualized management plans, promotion of patient self-management, continuity of care, and continuous monitoring of program outcomes and quality improvement.