The human nervous system possesses a variety of self-protective reflexes, especially concentrated in the craniofacial region, where cranial nerves (CNs) form the afferent and efferent limbs of reflex arcs through monosynaptic or oligosynaptic circuits within the brainstem. In surgeries where the CNs or brainstem are at risk of iatrogenic injury, intraoperative neurophysiological monitoring (IONM) typically utilizes free-run and triggered electromyography, often in conjunction with brainstem auditory evoked potentials, to map and monitor the CNs. However, electromyography has inherent limitations, sparking growing interest in utilizing brainstem reflexes to obtain intraoperative neurophysiologic data.