Intervertebral disc degeneration disease (IVDD) is one of the most common causes of lower back pain, significantly reducing individuals’ quality of life and placing a substantial economic burden on global healthcare systems. Lower back pain, one of the most prevalent musculoskeletal problems worldwide, affects more than 70% of the population at some point in their lives [1]. Progressive disc degeneration leads not only to mechanical instability [2] but also to pathological processes such as inflammation, sensitization of nerve endings, and nerve root compression [3]. Although traditional treatment methods—including physical therapy, pain management, anti-inflammatory drugs, epidural injections, and surgical interventions in advanced cases—provide symptomatic relief, they generally fail to reverse the underlying degenerative process [4].