Project-Based Learning (PBL) is a student-centred pedagogical methodology that promotes active learning by resolving real-world challenges. This study presents a case analysis of the implementation of PBL in the bachelor’s degree in Transport and Logistics Management (GGTL) at the Higher Technical School of Civil Engineering (ETSICCP), Polytechnic University of Valencia (UPV). The primary objectives of this research are: (1) to assess the effectiveness of PBL in developing essential professional competencies among logistics students; (2) to identify the benefits and challenges experienced during its implementation; and (3) to provide evidence-based recommendations to optimise future applications of PBL in higher education. A cross-disciplinary project involving four core subjects was used to simulate realistic logistics scenarios. Results reveal significant improvements in applied learning, teamwork, and decision-making skills, exposing difficulties in group coordination and equitable task distribution. This study contributes a structured framework for integrating PBL into logistics education and offers transferable insights for other academic programs seeking to enhance student engagement and professional readiness.