Climate change can be the driver for various variations in precipitation patterns in urban areas. These impacts of climatic change can cause amendments in quantity and quality of surface water. The present study is considered to review and evaluate various mitigation strategies for climatic variation in the context of drinking water. Vijayawada city in India is considered as a case study area, as the city is in the vicinity of the Krishna River. The characteristics of various surface water quality parameters of the Krishna River at the study area are assessed in terms of minimum and maximum values with regard to urbanisation of nearby Amaravati city from the year 2014. pH, DO, and total coliform are specifically exceeding tolerance limits as per standards. Also, other water quality parameters are showing an increasing trend subsequent to urbanisation. Further, impacts of climatic variation and more contamination, contributing to adverse outcomes of water quality, may be even applicable to drinking water. Thus, the water quality needs to be managed efficiently to provide safe drinking water in view of quantity and quality in urban areas.