There are two problems with methodology in psychology at large—the habit of treating methodology as if it were limited to any particular kind of method, and the inability to study complex dynamic processes of human lives. The first of these problems belongs to the area of social politics in the given area of science. The second is a genuinely epistemological obstacle that stems from the emphasis in the social sciences upon quanti-fictional analyses strategies, rather than on models of creative synthesis and development. Attachment of numbers to psychological phenomena that are pre-known to be of a qualitative kind is not creating science, but a new form of mysticism that parallels alchemy in the history of science. Psychology can become history-inclusive if it stops segregating complex phenomena into supposedly independent “variables” and looks for functioning structures. The functioning of these structures within irreversible time is the place of emergence of novelties. Cultural psychology adds to this focus on functioning structures the study of their organizing vehicles—signs—that guarantee massive explosions as well as constrictions of meaningfulness in social and personal lives.