This chapter focuses on the AI principle of transparency. Transparency is generally one-directional as a principle. Informed consent in medicine is always two-directional—the recipient of the information consents to or rejects the surgical procedure, drug, or other medical intervention. Informed consent is a handshake while transparency is an announcement. This chapter describes the types of disclosures necessary to achieve transparency, the limits of transparency, and the differences between transparency and explainability.