Two crucial facts have been established in the last chapter. The first is that African metaphysics does not play well with substance-based metaphysical frameworks. The second is that classical logic is inadequate for comprehending the African thought system. Incidentally, I must humbly admit that these two facts are not peculiar to African metaphysics, since prominent theorists of process metaphysics have voiced their concerns on these issues, in the history of Western thought. This chapter deals with the first whereas I deflect the second to the next chapter. On this note, I disclose how process metaphysics has emphasized change, dynamism, interdependence, relationality as the fundamental principles of reality over the quest for a perfect substance immune to change. In other words, the chapter uncovers how, in the history of Western thought, some of their philosophers have denied that that which is fixed and immutable, the perfect substance, should account for all of reality. I chronicle the ideas of six of these Western scholars, as evidence of conscious efforts to show traces of process thought in that tradition and the quest to break away from the hold and sway of the dominant style of doing metaphysics.