Liver resection is an effective treatment option for patients with hepatocellular carcinoma. However, posthepatectomy liver failure (PHLF) remains the leading cause of mortality following hepatectomy, and accurate PHLF prediction based on the preoperative liver functional reserve assessment is crucial. Liver function is estimated using various parameters, including routine blood biochemical assessments, clinical scoring systems, dynamic liver function tests, liver fibrosis markers, and imaging studies. This review aims to summarize the usefulness of current nonimaging tests for preoperative liver function assessment in predicting PHLF.