This paper focuses on spatial analysis at the district level in Slovakia to examine the relationship between regional environmental conditions and the number of projects implemented under the Operational Program Environment Quality (2014–2020). We performed a spatial analysis and visualization of the spatial distribution of 1601 environmental projects that were implemented in Slovakia in the 2014–2020 program period. These data were compared with environmental regionalization maps, which classify Slovakia into three primary areas based on environmental quality: pristine, moderately disturbed, and heavily disturbed environments. Spatial analysis, a key tool in geographic information systems (GIS), facilitates the identification of patterns, correlations, and relationships between geographical elements. The theoretical foundation of spatial analysis includes its ability to reveal spatial patterns and correlations that inform better planning and decision-making processes. The geo-analysis, which compared the spatial distribution of projects with the environmental status of regions, revealed that the number of approved projects does not correspond with the environmental condition of the respective regions. This finding suggests that factors influencing grant success may include various aspects beyond environmental quality, such as project proposal quality, information completeness, and alignment with regional needs. This result highlights the complexity of grant acquisition and the need for a multifaceted approach in evaluating project success.