This study seeks to evaluate the perceived usefulness and usability of an Electronic Medical Record (EMR) system in a college clinic context, emphasizing its role in assisting healthcare workers in providing effective patient care. Data were obtained from essential user roles, including physicians, nurses, and administrative personnel, using the Post-Study System Usability Questionnaire (PSSUQ). The results demonstrate that the system is seen as beneficial, evidenced by elevated scores in interface quality, indicated by a low mean value, which suggests satisfaction with the system. A significant positive association was seen between system usefulness and interface quality, suggesting that an effectively designed user interface substantially improves perceived utility. The study indicated a weak correlation between system usefulness and information quality, underscoring the need for enhancement in the accuracy, relevance, and presentation of the provided data. Nevertheless, the system was generally well-received by all user, who valued its effective user interface design and customizable features. These findings underscore the necessity of prioritizing interface quality in EMR systems while concurrently improving information quality to enhance user experience. The study’s findings enhance understanding of how usability factors affect the effectiveness of health information systems within a clinical setting.