Latest advances in the healthcare frontier utilize cloud computing and AI/ML to explore new methods for diagnosing and treating existing diseases. Further advances are expected as more medical data becomes available in the Cloud—the use of AI and ML-based solutions to identify hidden patterns in data yields previously unavailable insights. Doctors can better determine the course of treatment for patients by comparing a patient’s test results with datasets collected over time. We are on the verge of a perfect storm of medical data in the Cloud, with AI and ML solutions that will achieve breakthroughs like never seen before. This chapter presents several examples of this brewing revolution in medical treatments using the Cloud with AI and ML. The first example is of Heartflow, related to cardiovascular health. Second is a collaborative Cloud solution developed by Intel to facilitate cancer treatments. The third is related to multi-modal Glaucoma detection. We wrap up with a discussion on the emerging role of GenAI in healthcare.