Disinformation refers to the deliberate creation, dissemination, and amplification of false or misleading information with the intent to manipulate, influence, or deceive an audience. The study of disinformation has grown significantly in recent years due to its impact on political, social, and security domains. This research presents a bibliometric analysis to map global trends in disinformation studies, identifying leading contributors, thematic clusters, and the evolution of research in this field. A systematic search was conducted in the Clarivate Web of Science database using the keyword “disinformation,” yielding 5,047 research articles. The dataset was analyzed using VOSviewer to visualize bibliometric networks, co-authorship patterns, and keyword co-occurrences. The findings reveal that the United States, China, and the United Kingdom are the most influential contributors to disinformation research. Additionally, four major research domains emerged: (1) disinformation in political and societal contexts, (2) mechanisms of dissemination and detection, (3) disinformation’s impact on public health, particularly during the COVID-19 pandemic, and (4) theoretical and methodological studies. This study contributes to a deeper understanding of global disinformation research trends, providing insights into how scholarly efforts are distributed and which thematic areas are most explored. While offering a broad perspective on the field, a key limitation is the lack of focus on specific subdomains. Future research should narrow its scope to particular applications, such as political disinformation campaigns, military information warfare, or economic disinformation strategies.