Women who experience a pregnancy disorder characterized by uteroplacental malperfusion, such as pre-eclampsia, face up to six times higher risks of chronic hypertension, ischemic heart disease, stroke, and heart failure. With the greatest risks observed in the early postpartum period, pregnancy and the postpartum period provide a critical window of opportunity for early intervention to prevent long-term cardiovascular morbidity and mortality. However, despite extensive evidence on the increased risks among these young women, structured long-term cardiovascular follow-up is not widely offered, partly because of a lack of awareness, limited resources, and paucity of evidence on the optimal follow-up pathway. Nonetheless, several studies conducted in recent years have contributed to the development of evidence-based cardiovascular follow-up. Short-term blood pressure management postpartum, made affordable and feasible through remote self-monitoring, has shown promise in reversing adverse cardiac remodelling and improving outcomes. Postpartum prediction models using traditional and cardiac ultrasound parameters can aid in identifying which women are at highest risk, allowing targeted use of resources. Further studies are needed on the effect of monitoring and (lifestyle) interventions to provide a good evidence-based foundation for cardiovascular follow-up after a complicated pregnancy and to reduce cardiovascular morbidity and mortality in women.

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Cardiovascular Disease Later in Life

  • Renée J. Burger,
  • Basky Thilaganathan

摘要

Women who experience a pregnancy disorder characterized by uteroplacental malperfusion, such as pre-eclampsia, face up to six times higher risks of chronic hypertension, ischemic heart disease, stroke, and heart failure. With the greatest risks observed in the early postpartum period, pregnancy and the postpartum period provide a critical window of opportunity for early intervention to prevent long-term cardiovascular morbidity and mortality. However, despite extensive evidence on the increased risks among these young women, structured long-term cardiovascular follow-up is not widely offered, partly because of a lack of awareness, limited resources, and paucity of evidence on the optimal follow-up pathway. Nonetheless, several studies conducted in recent years have contributed to the development of evidence-based cardiovascular follow-up. Short-term blood pressure management postpartum, made affordable and feasible through remote self-monitoring, has shown promise in reversing adverse cardiac remodelling and improving outcomes. Postpartum prediction models using traditional and cardiac ultrasound parameters can aid in identifying which women are at highest risk, allowing targeted use of resources. Further studies are needed on the effect of monitoring and (lifestyle) interventions to provide a good evidence-based foundation for cardiovascular follow-up after a complicated pregnancy and to reduce cardiovascular morbidity and mortality in women.