The forthcoming EURO 7 regulation will impose limitations on brake wear particle emissions for both light-duty vehicles (LDVs) and heavy-duty vehicles (HDVs). While LDV testing is defined in UN GTR No. 24 (Global Technical Regulation), the test procedures for HDVs have not yet been defined. Assuming that HDV testing will utilize similar brake component test stands as LDVs, it is crucial to define a representative brake cycle to measure a realistic load profile. This paper explores the potential of using VECTO (Vehicle Energy Consumption calculation TOol), the official method used for HDV CO2 and energy consumption certification, adapted with real-world HDV driving data and an endurance brake model to enable the simulation of realistic brake behavior. Moreover, a methodology is described for the utilisation of the adjusted VECTO software in combination with the well validated and established target speed cycles used in VECTO to create a representative brake cycle that can be used for testing on a brake test stand. The target speed cycles were defined during the development phase of VECTO to depict representative speed and gradient profiles for different driving scenarios in Europe (urban, rural, and long-haul driving). The resulting candidate brake cycle was evaluated across four different HDV categories to investigate options and challenges for possible future test procedures, such as appropriate units for the brake wear limits or the need for different brake cycles due to varying mission profiles and brake specifications of the vehicles.