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During this nano-tech revolution period, carbon-based nanocompositesNanocomposites have transformed into revolutionary materials in tissue engineeringTissue engineering because they have strange mechanical, electrical, and biological properties. Usually, these nanocomposites contain carbon nanomaterials (CNMs) such as graphene, graphene oxide (GO), carbon nanotubes (CNTs), and carbon nanofibers, which are incorporated into biopolymeric or synthetic matrices to enhance their functional properties. This nanoscale architecture is close to the architecture which resembles the extracellular matrix (ECM), and thus, they are highly applicable to serve as scaffolds in bone, tissue healing of cartilage, neural, and cardiovascular. This chapter provides a great review of the synthesis methodologies, structural characterization, and biological property of the carbon-based nanocompositesNanocomposites to be used in the tissue engineeringTissue engineering. It is especially noted that they can improve mechanical robustness, electrical conductivity, and surface bioactivity when incorporated into hydrogels, electrospun nanofibers, or three-dimensional printed scaffolds. Moreover, the importance of surface modification and functionalization in regulating biocompatibility and in facilitating desired cell-material interactions are also discussed. Recent advancements related to the use of carbon-based nanocompositesNanocomposites in the delivery of bioactive agents, promoting angiogenesis and directing the differentiation of stem cells, are also mentioned. Although this has promising prospects, issues regarding cytotoxicity, long-term biodegradability, and the standardization of fabrication protocols are severe impediments to clinical translation. Overall, carbon-based nanocompositesNanocomposites present a highly flexible and promising candidate as the next-generation tissue engineeringTissue engineering tool. Continued investigations regarding their safe formulation and useful clinical application are prerequisite to the full utilization of their potential use in tissue repair and regeneration in varied biomedical applicationsBiomedical applications.

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Carbon-Based Nanocomposites: Advanced Materials for Tissue Engineering Applications

  • 章节

  • 发表日期：

    2026年

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  • Vaseem Raja,
  • Divya Katal,
  • Gunika Kour,
  • Sandeep Kaur,
  • Azad Qayoom Malik

摘要

During this nano-tech revolution period, carbon-based nanocompositesNanocomposites have transformed into revolutionary materials in tissue engineeringTissue engineering because they have strange mechanical, electrical, and biological properties. Usually, these nanocomposites contain carbon nanomaterials (CNMs) such as graphene, graphene oxide (GO), carbon nanotubes (CNTs), and carbon nanofibers, which are incorporated into biopolymeric or synthetic matrices to enhance their functional properties. This nanoscale architecture is close to the architecture which resembles the extracellular matrix (ECM), and thus, they are highly applicable to serve as scaffolds in bone, tissue healing of cartilage, neural, and cardiovascular. This chapter provides a great review of the synthesis methodologies, structural characterization, and biological property of the carbon-based nanocompositesNanocomposites to be used in the tissue engineeringTissue engineering. It is especially noted that they can improve mechanical robustness, electrical conductivity, and surface bioactivity when incorporated into hydrogels, electrospun nanofibers, or three-dimensional printed scaffolds. Moreover, the importance of surface modification and functionalization in regulating biocompatibility and in facilitating desired cell-material interactions are also discussed. Recent advancements related to the use of carbon-based nanocompositesNanocomposites in the delivery of bioactive agents, promoting angiogenesis and directing the differentiation of stem cells, are also mentioned. Although this has promising prospects, issues regarding cytotoxicity, long-term biodegradability, and the standardization of fabrication protocols are severe impediments to clinical translation. Overall, carbon-based nanocompositesNanocomposites present a highly flexible and promising candidate as the next-generation tissue engineeringTissue engineering tool. Continued investigations regarding their safe formulation and useful clinical application are prerequisite to the full utilization of their potential use in tissue repair and regeneration in varied biomedical applicationsBiomedical applications.