Latinx students face numerous systemic barriers to accessing and succeeding in higher education. These barriers largely arise because higher education is rooted in Eurocentric practices that tend to be culturally incongruent with values held by many Latinx students, limited mentorship and community, and financial constraints. In this chapter, we provide an overview of culturally responsive pedagogical practices. We focus on inclusive classroom teaching, modifications to the curriculum to make it more culturally relevant, and holistic mentorship that fosters a sense of belonging, engagement, and promotes student success. In so doing, we draw on the numerous cultural values and strengths Latinxs bring to higher education and how instructors can tap into those strengths as they frame assignments and research competencies. We end with a description of the power of liberation mentorship for promoting the well-being and advancement of US-residing Latinx students pursuing degrees in psychology.