This paper provides insight in the response of a 20-storey steel structure subjected to recurring seismic and wind loads, through collapse. The seismic and wind assessment performance framework applied herein, is based on the comprehensive procedures recommended by FEMA P695 and the ASCE Prestandard for Performance-Based Wind Design. The far-field FEMA set of strong ground motion excitation is used for seismic simulations. Alongwind and crosswind loads, derived from local aerodynamic data available at the Tokyo Polytechnic aerodynamic database, are used in wind simulations. Detailed, lumped plasticity models of the lateral force resisting system are developed in OpenSees. The numerical models are used to perform nonlinear simulations that predict with sufficient accuracy the multi-hazard structural performance, through collapse. Seismic and wind Incremental Dynamic Analyses provide insight into the near collapse behaviour of the building and allow quantification of the margin of safety against collapse under extreme events. System performance is quantified in terms of peak drift, floor acceleration, and residual drift. The building, fails to meet drift and acceleration criteria under service level winds. The near collapse structural response under very strong motion excitation is characterised by significant damage, distributed over multiple stories; whereas damage under ultimate wind loads is limited at the lower floors, where wind demands are dominant. Yielding under alongwind and crosswind loads occurs for events characterised by high (compared to design) wind speeds. The results reinforce the belief that wind design would benefit greatly from the introduction of limited inelasticity and inherent overstrength.