Perseris® is the first subcutaneous long-acting injectable (LAI) risperidone product. As of July 2024, the marketing and sale of the medication have ceased. Per Indivior, the manufacturing of the medication was discontinued in May 2025. The final product has an expiration date of October 2026. After this date, the medication will no longer be available on the market in the United States. This chapter provides clinical pearls on how to appropriately prescribe and administer Perseris®.

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Risperidone for Extended-Release Injectable Suspension (Perseris®): Second-Generation Antipsychotic Long-Acting Injectable

  • Megan J. Ehret

摘要

Perseris® is the first subcutaneous long-acting injectable (LAI) risperidone product. As of July 2024, the marketing and sale of the medication have ceased. Per Indivior, the manufacturing of the medication was discontinued in May 2025. The final product has an expiration date of October 2026. After this date, the medication will no longer be available on the market in the United States. This chapter provides clinical pearls on how to appropriately prescribe and administer Perseris®.