This chapter presents a structured case study approach to analysing how science interacts with policy-making, particularly under the challenging conditions of uncertainty, high stakes, and conflicting values—key features of “post-normal science” (PNS). The case studies are designed to be used as a classroom and individual learning tool and for those following emerging science for policy controversies. The case study framework considers elements such as scientific uncertainty, stakeholder interests, epistemic community dynamics, and political context. Students can analyse how decisions are influenced not just by evidence, but by who produces it, how it is communicated, and who controls the policy narrative. The infamous British Bovine Spongiform Encephalopathy (BSE) crisis is used as an example case, to illustrate how epistemic differences between scientific communities, political pressures, and poor risk communication can delay action and erode public trust. The chapter also introduces a “post-normal cataloguePost-normal catalogue"” tool for mapping how features such as CUDOS violations, exclusion of lay voices, and politicisation of science influence outcomes. This analytic model empowers readers to interpret and compare cases where science meets policy, enabling readers to navigate the complexities of science-policy interactions more effectively. The chapter includes another 9 complete or incomplete case studies using the new framework. Incomplete studies and the PNS checklist can be used in the classroom as active learning tools.