This study addresses the challenge of improving reading comprehension in secondary students within rural educational contexts, where traditional methods often fail to foster interpretation and critical thinking. It evaluates the impact of ICT-mediated collaborative strategies on reading performance in Language and Literature. A quasi-experimental design was applied in an Ecuadorian public school, involving 180 students divided into experimental and control groups. The experimental group engaged in eight weeks of interactive activities using digital tools such as Genially, Padlet, and Storyjumper. Results showed a significant improvement in the experimental group’s performance (from 6.4 to 8.1 average), along with increased motivation and classroom engagement. These findings confirm the effectiveness of integrating collaborative digital strategies to enhance reading comprehension. The originality of this study lies in its contextualized application of ICT tools at the secondary level, offering scalable pedagogical insights for broader educational innovation.