The present paper presents the experience of the “Child, Adolescent, Family” department of Mental Health Institute Galen, Athens, Greece regarding the transition from in-person therapy to Telepherapy do to the lockdown caused by the COVID pandemic. It consists of a detailed account of (a) the Institute’s preparation and the supportive framework it provided so that therapists could adapt and perform within this new clinical practice; (b) the reactions of parents, children, adolescents, psychotherapists and the Institution itself. A separate chapter extensively outlines the particularities that emerged during the practice of telepsychotherapy with “negative” connotations, such as the activation of the perpetual level, the difficulties that assispsychotherapists experienced in free association and in the formulation of interpretations, the mourning of the loss of the illusion of a’‘complete relationship’‘that is offered by the physical presence of the meeting, as well as those with “positive” connotations, such as the mobilization of the parents as the children’s, the adolescents’, and the therapists’ “assistants,” the more active attitude of the therapists in the online session, their increasing resourcefulness, the affirmation of the value of the speech over the image.