This study aims to investigate the impact of market volatility and environmental, social, and governance factors on the profitability of information technology companies, focusing on key financial indicators. Given the current economic climate, marked by uncertainty and rapid changes, thus, this topic is highly relevant. The study examines a two-decade span from 2005 to 2024 and employs a rigorous quantitative methodology. Using advanced econometric regression models, the research provides a comprehensive understanding of the interactions between financial performance and external factors. This study finds that environmental, social, and governance factors and S&P 500 index dynamics enhance performance, while exchange rate fluctuations negatively affect it. The findings inform risk management, financial decisions, and performance optimization, strengthening investor confidence and corporate sustainability.