The GREEN-LOG Digital Control Tower is an innovative solution designed to tackle the growing challenges of urban last-mile logistics caused by e-commerce expansion. This integrated platform offers real-time monitoring of delivery assets, near real-time forecasting of transport demand and supply, and advanced data-driven analytics to enhance operational coordination across complex delivery ecosystems. Leveraging AI-powered predictive models, dynamic multi-modal routing, and Logistics-as-a-Service (LaaS) marketplace metrics, the system improves situational awareness, accommodates consumer demand evolution, and supports informed decision-making for logistics service providers and city authorities. The platform has been designed to promote environmentally responsible practices, leading to reducing carbon emissions and urban traffic congestion while increasing delivery efficiency and reliability. Its flexible and modular architecture enables deployment across diverse European urban contexts. This chapter presents the system’s core components, implementation strategies, and business value, illustrated through detailed case studies and performance metrics. Through these insights, the chapter demonstrates how the GREEN-LOG Digital Control Tower fosters sustainable, efficient, and resilient urban last-mile delivery ecosystems.