Environmental pollution from anthropogenic activities is a global concern requiring innovative treatment solutions. This chapter explores the application of nature-based technologies for treating hazardous contaminants in wastewater. By harnessing the inherent capabilities of nature, strategies, like constructed wetlands, phytoremediation, biofiltration, and bioremediation, offer effective pollutant mitigation. Emerging approaches, such as floating treatment wetlands, algal biotechnology, and sustainable aquaculture systems, are also examined for their potential to redefine wastewater treatment paradigms. Through real-world case studies and the latest research, this chapter illustrates the practical applications and benefits of these methods, highlighting their environmental advantages, cost-effectiveness, and adaptability across diverse contexts. The focus on nature-based technologies emphasizes their role in fostering ecological resilience and sustainability, making them vital tools for mitigating the environmental and health risks associated with hazardous wastewater. This chapter serves as a valuable resource for those seeking holistic and sustainable wastewater treatment solutions.