During the reign of king Aśoka Maurya (c. 304–232 BC; r. 268–232 BC), the teachings and practices of Buddhism were brought to the fringes of the Mauryan Empire and its neighbouring kingdoms. This included the regions to the northwest of the Hindukush, the land of Yonas. According to current scholarly consensus, the primary evidence for the transmission of Buddhism into Central Asia and the activities that took place during this early period are the inscriptions attributed to Aśoka and the fifth–sixth century AD Pāli Dīpavaṃsa and Mahāvaṃsa. The Italian Archaeological Mission in Pakistan (MAIP) has recently unearthed an apsidal temple in Barikot that dates to the time of the Indo-Greeks, and potentially even as far back as Aśoka’s time. This early devotional space, paired with the early stūpa at Butkara 1, presents the most important physical evidence for pre-Kuṣāṇa Buddhist practice along the overland travel routes to Central Asia. Considering how Buddhism became a major, living tradition in Central Asia from the Kuṣāṇa period onwards, these early dates support the integration of Buddhist practitioners into Indo-Greek and Graeco-Bactrian communities. This chapter presents a theoretical model for Early Buddhist integration into Central Asian multireligious spaces, particularly focusing on the Hellenistic city of Ai Khanoum.